Familial spontaneous pneumothorax.

Risk Factors of Pneumothorax at Aleppo University Hospitals

Spontaneous pneumothorax can be either primary due to the rupture of subpleural bleb or secondary due to underlying lung disease, usually bullous emphysema.1 Relatively little is known about the causative factors of spontaneous pneumothorax in Arab Countries.1 This is the first study and the primary step towards understanding the risk factors and causes of spontaneous pneumothorax in Syria.Syri...

Concurrent spontaneous pneumothorax in identical twins.

The common cause of simple pneumothorax is rupture of an emphysematous bleb or bulla. The aetiology of these is uncertain. A familial predisposition has previously been suggested' and we report the incidence of concurrent spontaneous pneumothoraces in identical twins. We have found no previous report in the English literature of concurrent spontaneous pneumothorax in identical twins treated sub...

α1-antitrypsin deficiency in fraternal twins born with familial spontaneous pneumothorax.

We report a case of spontaneous familial pneumothorax in fraternal twin boys. The twins' family history is remarkable for reactive airway disease and a female sibling also born with spontaneous pneumothorax. The family had no history of connective tissue disorders, renal cancer, or dermatologic diseases. Analysis of the twins' α(1)-antitrypsin (AAT) genotype, phenotype, and serum concentration ...

Familial spontaneous pneumothorax.

In a three generation family with 27 members we examined a relationship could be found between spontaneous pneumothorax and HLA-haplotypes, alpha 1-antitrypsin phenotypes or concentration or lung volumes and ventilatory capacity. Eight individuals in the family suffered from spontaneous pneumothorax. No relationship with the investigated markers could be found in this informative family. All pa...

Familial Spontaneous Pneumothorax.